Fertility saving study
    Inclusion critera
        Cervical cancer (any histology, any stage from T1a1) [No,Yes]
        Fertility sparing treatment (FST) with the aim to preserve uterus (any procedure, at least attempt) [No,Yes]
        Information of the outcome available (follow-up available) [No,Yes]
    Patient's data
        Date of birth (month/year)
        Parity before diagnosis
        Previous gynecological surgery before cervical cancer diagnosis [No,Yes]
            Date of surgery (YYYY)
            Type of surgery
    Diagnosis and diagnostic work-up
        Date of first diagnosis of cervical cancer (month/year)
        Diagnostic procedure
        Histology
            Histological type
            Grade
            LVSI
        Pre-treatment work-up
            CT scan [No,Yes]
            Colposcopy [No,Yes]
            Cystoscopy [No,Yes]
            DW-MRI [No,Yes]
            MRI [No,Yes]
            PET-CT [No,Yes]
            PET-MRI [No,Yes]
            Rectoscopy or colonoscopy [No,Yes]
            Ultrasound [No,Yes]
        Pre-treatment clinical and radiological stage (TNM classification)
    Primary treatment
        Neoadjuvant chemotherapy (before the FST procedure) [No,Yes]
            No of cycles
        Surgical treatment
            Cervical procedure
                Date of procedure (month/year)
                Type of procedure
            Repeated cervical procedure (after FST) [No,Yes]
                Date of procedure (month/year)
                Reason
                Description of other reason
                Type of procedure
            Lymph node procedure
                Sentinel lymph node biopsy [No,Yes]
                    Date of procedure (month/year)
                    Total number of sentinel nodes
                    Detection
                    Methods of mapping
                        Blue dye [No,Yes]
                        Indocyanin green [No,Yes]
                        Technecium [No,Yes]
                Pelvic lymphadenectomy [No,Yes]
                    Date of procedure (month/year)
                    Total number of pelvic nodes (including sentinel nodes if done)
                Paraaortic lymphadenectomy [No,Yes]
                    Date of procedure (month/year)
                    Total number of paraaortic nodes
            Cerclage placement
                Date of cerclage (month/year)
                Timing of placement
                Type of cerclage
        Adjuvant chemotherapy (after treatment procedure) [No,Yes]
            No of cycles
        Definitive histology (after surgical treatment procedure)
            Size of the tumor
                horizontal spread / horizontal (AP)
                stomal invasion / vertical (CC)
                latero-lateral (LL)
            Size of the cone or trachelectomy specimen
                N/A [No,Yes]
                Lenght (the distance from the external margin to the proximal/internal margin)
                Thickness (the distance from the stromal margin to the surface of specimen)
            Lymph nodes - histology
                Only sentinel node(s)
                Other pelvic (and paraaortic) nodes (if sentinel node biopsy was performed)
                Only pelvic (and paraaortic) nodes (if sentinel node biopsy was not performed)
    Follow-up & recurrence
        Oncological treatment (hysterectomy, radiotherapy, chemotherapy) during the follow-up period was given
        Oncological treatment (hysterectomy, radiotherapy, chemotherapy) during the follow-up period
            Date of treatment (month/year)
            Reason
                Abnormal Pap smear [No,Yes]
                Cervical cancer recurrence [No,Yes]
                Cervical stenosis/hematometra [No,Yes]
                Doctor's decision (no disease suspected) [No,Yes]
                HPV positivity [No,Yes]
                Other [No,Yes]
                Patient's decision (no disease suspected) [No,Yes]
                Pre-cancer-recurrence (any proven LSIL, HSIL or AIS) [No,Yes]
                Second cancer (endometrial, ovarian etc.) [No,Yes]
            Type of treatment
                Chemotherapy [No,Yes]
                Hysterectomy [No,Yes]
                Radiotherapy [No,Yes]
        Follow-up procedure
            Biopsy [No,Yes]
                1. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                2. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                3. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                4. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                5. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
            CT [No,Yes]
                1. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                2. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                3. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                4. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                5. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
            Colposcopy [No,Yes]
                1. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                2. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                3. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                4. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                5. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
            HPV test [No,Yes]
                1. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                2. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                3. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                4. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                5. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
            MRI [No,Yes]
                1. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                2. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                3. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                4. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                5. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
            Others [No,Yes]
                Procedures description
            PET-CT [No,Yes]
                1. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                2. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                3. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                4. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                5. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
            Pap smear [No,Yes]
                1. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                2. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                3. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                4. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                5. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
            Physical examination [No,Yes]
                1. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                2. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                3. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                4. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                5. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
            US [No,Yes]
                1. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                2. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                3. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                4. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
                5. year [No,Yes]
                    If clinically indicated [No,Yes]
                    Routinely [No,Yes]
                        Frequency every
        Date of last follow-up (month/year)
        Pregnancy after primary treatment
            Attempt to concieve [No,Yes]
                More than 6 months [No,Yes]
                Way of conception
                    IVF program [No,Yes]
                    Natural [No,Yes]
            Pregnancy after treatment
                Number of pregnancies
                Number of abortions
                Number of deliveries
            Profylactic management during pregnancy [No,Yes]
                Antibiotic treatment [No,Yes]
                None [No,Yes]
                Other [No,Yes]
                    Description of the profylactic procedure
                Preventive hospitalisation [No,Yes]
                Profylactic cerclage during pregnancy [No,Yes]
                Profylactic tocolytic therapy [No,Yes]
                Progesterone administration [No,Yes]
                Regular US cervicometry [No,Yes]
            Delivery (complete repeatedly for each delivery) [No,Yes]
                1. delivery [No,Yes]
                    Method of delivery
                    Date of delivery (month/year)
                2. delivery [No,Yes]
                    Method of delivery
                    Date of delivery (month/year)
                3. delivery [No,Yes]
                    Method of delivery
                    Date of delivery (month/year)
                4. delivery [No,Yes]
                    Method of delivery
                    Date of delivery (month/year)
                5. delivery [No,Yes]
                    Method of delivery
                    Date of delivery (month/year)
        Recurrence
            Pre-cancer recurrence during the follow-up [No,Yes]
                Pre-cancer histotype
            Cancer recurrence [No,Yes]
                Disease free interval (DFI)
                Location
                    Cervix [No,Yes]
                    Distant - others [No,Yes]
                        Description
                    Distant abdomen [No,Yes]
                    Distant thorax [No,Yes]
                    Paraaortic lymph nodes [No,Yes]
                    Parametrium [No,Yes]
                    Pelvic lymph nodes [No,Yes]
                    Pelvis - others [No,Yes]
                        Description
                    Vagina [No,Yes]
                Symptoms of recurrence [No,Yes]
                    Description
            Main (or first) method(s) of recurrence detection
                Biopsy [No,Yes]
                CT [No,Yes]
                Clinical symptoms [No,Yes]
                Colposcopy [No,Yes]
                Cytology [No,Yes]
                Gynecological examination [No,Yes]
                HPV test [No,Yes]
                MRI [No,Yes]
                Others [No,Yes]
                    Description of procedures
                PET-CT [No,Yes]
                Physical examination [No,Yes]
                US [No,Yes]
        Current status
        Date of death (month/year)
        Cause of death